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Rather, we believe that oral sleep apnea appliances, when prescribed by a practitioner for the treatment of a medical condition such as obstructive sleep apnea, as medically reasonable and necessary and therefore may be payable by Medicare

Empirical testing could include assessing whether there are rapid or unprecedented changes to patient case volume or case mix, and the extent to which this could lead to misleading or inaccurate results (86 FR 65508)

During spermatogenesis, DNA methylation has been reported to modulate the expression of numerous germ cell-specific genes, such as Lin28a and Nanos2 15