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The disruption of the stop signals can be caused by genetic, or inherited, defects in the cells DNA , or by external dangers such as radiation or environmental toxins, such as pollutants or chemicals, both of which can cause damage to the cells DNA
Nat Rev Cancer (2003) 3:73344
However, there are more studies every day that caution users about the harmful ingredients, including nicotine, heavy metals and flavourings that become toxic when heated and bonded with other chemicals
Even after citing its benefits, Worthen has difficulty communicating snuff's allure to his friends
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