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Using low nicotine liquids in more powerful devices works best with e-liquids that have a higher Vegetable Glycerine (VG) content, which complements the stronger throat hit that freebase nicotine provides

It can even cause infertility (the inability to have children)

Owing to this law, vape flavor manufacturers in California must submit a legally binding declaration that proves their products are unflavored, and any vapable product not included on this list will be considered illegal, and manufacturers and distributors face substantial penalties for non-compliance

It is unlikely this long-ago medical practice could have inspired the idiom at so late a date