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It has also been shown that cbNPs accumulate in antigen-presenting dendritic cells derived from emphysematous lung tissue of smokers [73] and that cigarette smoke triggers the NLRP3 inflammasome [63], which is again consistent with the observation that IL-1 levels are elevated in smokers lungs [19]

VLN cigarettes could be on the market in as many as 18 US states within the next 12 months, manufacturer 22nd Century Group said during the presentation of its third quarter results

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