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The study revealed that at the 12-month follow-up, 61.9% of those who had given up smoking completely and taken up vaping managed to keep from going back to tobacco cigarettes, while only 20.6% of smokers and 22% of dual users managed to reach the goal of complete abstinence from tobacco

Research studies in adults have found the amount of nicotine from e-cigarettes is in varying doses ranging from slight to as large.[14] Evidence from several decades has demonstrated nicotine as a highly addictive chemical compound that can change the way the brain works and cause physical and psychological dependence

It considers not only the overlapping region of the object boxes but also the non-overlapping regions, providing a better measure of overlap