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5.2 MRGPRX2: an emerging pruritogenic target MRGPRX2 is a member of the G protein-coupled receptor (GPCR) superfamily and functions as a critical signaling hub that links extracellular stimuli to intracellular responses (152, 153)

Cotinine and zonulin emerged as independent predictors of LPS, reinforcing the connection between nicotine exposure, gut permeability, and oxidative stress

Over-the-counter options include: Aspirin Advil (ibuprofen) Aleve (naproxen) Tylenol (acetaminophen) These medicines are very effective at controlling sore throat pain

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