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Philip Morris International, which makes and distributes Marlboro cigarettes everywhere in the world aside from the United States, is eyeing alternative reduced risk alternatives to smoking, already pouring more than $3 billion and a decade of research into developing less-harmful products

While there are no prospective studies assessing the direct reproductive effects of e-cigarette use on ART outcomes, studies have suggested that the use of e-cigarettes can provide levels of nicotine and other metabolites that are similar to those produced by traditional cigarettes [9,17,29,30,31,32,33,92]

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