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When DNA strands break, there is a chance that the cell will become malignantly cancerous

[40] These processes include the following: Acute eosinophilic pneumonia [40] COVID-19 [17] [18] [19] [68] [69] [70] [71] Diffuse alveolar hemorrhage [40] [5] Giant cell pneumonitis [5] Hypersensitivity pneumonitis [40] [5] Lipoid pneumonia [66] [5] Organizing pneumonia [40] [5] Respiratory bronchiolitis interstitial lung disease [40] The use of imaging and other diagnostic modalities, including chest CT, bronchoscopy with bronchoalveolar lavage, and lung biopsy, may provide additional information to determine the presence of these processes and potentially establish a definitive diagnosis, but are generally not performed unless clinically indicated

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109 After one extension, the comment period closed in July 2018 and the agency had received over 500,000 comments