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However, there still may be some bias (toward a positive association) from including all smoking status groups in the same model, especially if there is an unaccounted-for interactive effect between EC use and smoking history (such that those with longer smoking histories have higher health risks) which could falsely appear to carry over to PWNS
In 2019, there were an estimated 155 million smokers aged between 15 and 24 years equivalent to 20.1% of young men and 5.0% of young women, globally
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