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Understanding the immunological consequences of inhaled cannabis products is further complicated by the diversity of products, lack of standardized preclinical models that recapitulate human use patterns and the variation in THC levels that has occurred in cannabis over time

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This should be taken further in light of the evidence that the enactment of smoke-free legislation has been associated with an increased consumption of smokeless tobacco among adolescent males 25

Figure 1 shows the US tobacco industry data visualization based on 2022 data for the market shares and 2024 for other industry information