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Common effects among long-term inhalant users include: Apathy Muscle spasms Irritability Anxiety and depression Organ damage (lungs, liver, kidney, heart, etc.) Brain damage Amnesia Loss of senses Heart failure Damage to bone marrow Diminished intelligence Coma Addiction Death Chronic use of inhalants can also harm organs, such as the kidneys and liver, which work to rid the body of toxic substances