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At present, biomarkers of airway remodeling in asthma can be obtained from various sources such as urine, blood, bronchoalveolar lavage fluid, induced sputum, exhaled air agglutination, bronchial biopsy, and some scholars even proposed that imaging technologies can also act as markers 93

These factors, combined with the already harmful effects of alcohol on the liver, result in a more pronounced risk for women in developing ALD when they smoke, highlighting gender-specific susceptibility

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