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As newer iterations brought higher levels of nicotine in an increasing array of flavors and product designs, youth use skyrocketed

Toxic effects of nicotine include: Triggering acute increases in heart rate and blood pressure Impairing the ability of blood vessels to expand and contract as needed Promoting blood clots, which increases risk of heart attack and stroke Causing scarring to the heart Promoting growth of new blood vessels, which can feed cancers The highly addictive nature of nicotine ensures that all of these toxic effects will be endured repeatedly and over the long term, researchers concluded

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Molecular crosstalk between herbal phytochemicals and microRNAs in electronic cigarette vapor: Implications for respiratory health Putri Cahaya Situmorang, Helen Helen, Syafruddin Ilyas, Pandu Surya Pangestu, Syahputra Wibowo, Kaniwa Berliani, Alexander Patera Nugraha, Khatarina Meldawati Pasaribu Fitoterapia 21