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People with this condition may experience: Difficulty opening the mouth Burning sensation in the mouth Stiffness in the cheeks Difficulty swallowing food Oral submucous fibrosis is considered a precancerous condition, which means it can increase the risk of developing oral cancer if not treated early

A poor-rated meta-analysis of 32 global studies estimated 1.7 million disability-adjusted life years (DALYs) lost and 62,283 deaths in 2010 globally from cancers of the mouth, pharynx and oesophagus attributed to SLT-product [14]

These are concerning trends given that cannabis has potentially dangerous effects on young people

Nicotine reacts with the corticotropin-releasing factor (CRF) in your hypothalamus, which reacts with the HPA Axis to create cortisol