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E-Cigarettes are an Alternative to Smoking E-cigarettes are another kind of smoking alternative, but they do not utilise real tobacco

Canadian Cancer Society, 2025

The ROS is a single summary of the effect of smoking on the outcome, with higher positive ROSs corresponding to stronger and more consistent evidence and a higher average effect size of smoking and a negative ROS, suggesting that, based on the available evidence, there is no significant effect of smoking on the outcome after accounting for between-study heterogeneity

Tobacco-specific nitrosamines are among the most potent carcinogens unique to tobacco products