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Substance-use disorder: A diagnostic term in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) referring to recurrent use of alcohol or other drugs that causes clinically and functionally significant impairment, such as health problems, disability, and failure to meet major responsibilities at work, school, or home
Cancer 118 (11), 27442749
He told me that he was on a new heart medicine and that his legs had been drained of most of their excess fluid
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