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Physical dependence - when your body requires nicotine to prevent the uncomfortable feelings that come with stopping use
Population density, land use, limited access for cleaning, and waste collection regulations also affect the density of CBs and, consequently, the pollution index 32
PMI responded by launching BONDS by IQOS in Italy in 2026 to reach adult smokers who had been harder to convert
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![smokeless form of tobacco Fig. 2.1.2, [Examples products,...]](https://www.ncbi.nlm.nih.gov/books/NBK606465/bin/978-92-832-0448-0-C-F2.1.2.jpg)
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