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News reports have shown that the devices do occasionally malfunction, starting fires in homes and cars and causing serious injury to users or those around them

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However, as discussed below, this finding is most plausibly explained by healthy switcher bias, residual confounding by age, body mass index, and other unmeasured factors, and the variable and uncontrollable effects of prior tobacco exposure in the vaping group, rather than by any protective effect of e-cigarette use