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Usually, the more severe COPD symptoms are, the inflammation of the airway is also correspondingly increased and continues after smoking cessation ( Figure 1 3 Characteristics of inflammation associated with COPD Patients with COPD often have a characteristic inflammatory pattern, with a significant increase in the number of macrophages, neutrophils, T lymphocytes and B lymphocytes in airway secretions ( 3.1 Inflammatory cells The formation of lung inflammation in patients with COPD is mainly associated with congenital and adaptive immunity, among them, the congenital immune contains neutrophils and macrophages, eosinophils and mast cells, natural killer cells, T cells, such as inflammation, fine dominant immune response, adaptive immunity refers to T and B lymphocytes or dominant immune response

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Cons: Potential for Harshness: If used too heavily, the intense flavor and nicotine content can become overwhelming or irritating to the throat