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He also points out the immediate discomforts, like coughing and spitting, as clear signs of its inherent harmfulness

Once nicotine gets to the brain, it stimulates the release of neurotransmitters, and it is the release of dopamine, a 'reward chemical', that is responsible for the addictive effects of nicotine

He liked to use extreme settings on the pedals so his signal would hit the input stage of his amps really hot