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Although there is no exact geno-phenotypic correlation, patients with pathogenic variants in TGM1 associate alopecia, ectropion, and neonatal presentation as a collodion baby with a significantly higher frequency than the other genes.8 Ceramide synthesis pathway in the epidermis

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Close monitoring of the patients vital signs, including oxygen saturation, heart rate, blood pressure, and respiratory rate, is essential during the entire procedure