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5 September 2020 : Continuing concerns about nitrosamine impurities in medications (e.g., metformin, a diabetes medication, and ranitidine, a heartburn medication) prompted the FDA to set an acceptable daily intake limit (AI) for varenicline nitrosamine impurities at 37 nanograms

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Over follow-up, incident metabolic syndrome was defined when the total number of components reached three over at least one year of follow-up

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