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Large puffs dominate the Middle Eastern market, with advanced and disposable products coexisting Potti Lan notes that the number of puffs on the Middle Eastern market has progressively increased from 2,000 to 3,000 and 4,000, that the number of disposable puffs is now approaching 8,000, and that there are even products with more than 12,000 puffs

The placement of each capsule must ensure that activating one does not inadvertently rupture the other, which requires precise inter-capsule spacing calibrated during the production process

The Institutional Review Board of the University of Arkansas approved all procedures