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Multiple observations have also supported early impairments in arterial stiffness following acute consumption of ENDS containing nicotine [24, 30, 80], even after very short periods of usage [82]

Its an interesting method of trying to discourage smoking, vaping, chews, pouches and the like: anyone already old enough to walk into a store and buy cigarettes would be able to keep doing so, but people who have not yet hit the legal age for tobacco sales (21) would never be able to legally buy it in Massachusetts