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Black Note e-liquids are made with four ingredients: naturally extracted tobacco, pharmaceutical-grade vegetable glycerin, pharmaceutical-grade propylene glycol, and nicotine (in nicotine-containing variants)

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The first official anti-smoking programs launched in Italy in 1981 and proliferated through the decade and beyond

Several articles over the last 20 years have reported a correlation between cannabis smoking and apical emphysema with large bullae formation, specifically in younger patients 3,5,6 This phenomenon has been referred to as "marijuana lung"