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Its a great question because we do get a lot of the same questions

Researchers at the University of California, San Francisco, and University of Alabama at Birmingham knew tobacco smoking causes lung damage and leads to respiratory issues such as chronic obstructive pulmonary disease (COPD), but they wanted to be clear whether smoking marijuana, had similar effects

Furthermore, the association of CR with altered urea cycle activity is supported by recent studies showing that creatinine levels and creatine phosphocreatine pathway activity are regulated by urea cycle activity (44)