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& Bejder, J

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IGF-1 availability is tightly regulated by the so-called insulin- like growth factor binding proteins (IGFBPs), which may act by increasing IGF-1 half-life, from minutes to hours (most commonly by forming a tertiary complex with Acid-Labile Subunit and IGFBP3), however blocking its binding to the insulin-like growth factor 1 receptor (IGF- 1R) [7]

10.1210/jcem.84.7.5853 Summary Keywords hormone, resistance exercise, muscle growth, protein synthesis, hypertrophy Citation Gharahdaghi N, Phillips BE, Szewczyk NJ, Smith K, Wilkinson DJ and Atherton PJ (2021) Links Between Testosterone, Oestrogen, and the Growth Hormone/Insulin-Like Growth Factor Axis and Resistance Exercise Muscle Adaptations