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Long-term toxicity Continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose

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Many Canadians report significant pain reduction within the first two weeks of consistent use

That question originated in an Australian university laboratory, was carried into a commercial development program with a stabilized analogue, tested in a series of controlled human trials, and ultimately routed away from drug registration and toward a US dietary-ingredient determination