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But the null finding is notable because it suggests that GLP-1 appetite suppression may already be near the ceiling of what appetite reduction can achieve, leaving little room for phentermine to add benefit

Ozempic (semaglutide) 0.25 mg, 0.5 mg, 1 mg, and 2 mg injection pens, which are approved as treatments for Type 2 diabetes, will also be available for eligible patients based on individual clinical judgment

The use of a single interim analysis in the SELECT trial reduces the risk of bias compared to multiple interim tests in a trial that uses the group sequential design

Manage stress through relaxation techniques or therapy to reduce cramp risk