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Reference: (1) P.Sikiric et al (2016) Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications Current Neuropharmacology, 2016;14(8):857-865

In current study, we used newly developed monoclonal antibody that has previously been validated as specific for GLP-1R [24] and demonstrated that the protein levels of GLP-1Rs in the pelvis are greater in HF than Sham, suggesting that enhanced expression of GLP-1R in the pelvis leads to enhanced activation of afferent renal nerves in rats with HF