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Sometimes it's even a little slower because we use microdosing

We found that both glibenclamide- and gliclazide-induced stimulation of insulin secretion was significantly impaired in the Barr2 mutant islets, as compared with WT control islets (Supplemental Figure 13)

These are elements such as the amount of fat to be treated and individual response to the treatment

Understanding why they complement each other is more useful than simply following a trend, especially if you are deciding whether to add the second to a stack you already run