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Some contributors to PCOS include: A diet high in sugars and refined carbohydrates Chronic, low-grade inflammation Gut dysbiosis (imbalance in gut bacteria) Hormonal imbalances caused by excess male hormones

Similar content being viewed by others Introduction Lifestyle and eating habits have changed significantly over the years, driven by shifts from traditional whole foods to a higher consumption of processed foods, increased convenience and snacking, along with the influence of technological advancements and globalization on food availability and consumption patterns [1,2,3]

This upregulated the functional subunits of SLC7A11 and System Xc-, protecting RA-FLSs from oxidative stress and excess iron, thereby inhibiting ferroptosis