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Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimers disease

[239] found the essential oil of ZBE treatment could decrease the expression of vascular cell adhesion molecule-1 (VCAM-1), TLR8, IL-1 and IL-11 mRNA, which are involved in these potential genetic pathways

Furthermore, studies have demonstrated that elevated AMPK expression can modulate downstream protein expression, resulting in reduced levels of sterol regulatory element-binding protein (SREBP), which subsequently decreases fatty acid synthase (FAS) expression and suppresses lipogenesis 37