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Because both influence hepatic metabolism, so the article says baseline impairment raises the risk of adverse effects from the combination

Review of the effects and mechanism of curcumin in the treatment of inflammatory bowel disease

So she decided to take another, not realizing that some edibles take hours to kick in

Gastroenterology 122(5):13991410 De Minicis S, Seki E, Oesterreicher C, Schnabl B, Schwabe RF, Brenner DA (2008) Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells