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Feature / Melanotan MT@ / PT-1414 Origin / MC1R, MC3R, MC4R / MC3R, MC4R Focus / Pigmentation + CNS / CNS signaling Selectivity / Broder / More Selective MT2 is often used in broader receptor studies, while PT-141 is studied for more targeted neurological effects

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1a) can be subdivided into a reductive half-reaction (electrons flow from NADPH to the enzyme) and an oxidative half-reaction (electrons from the enzyme are transferred to the oxidizing substrates) 17