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For the MMRM analysis, 309 participants who completed Part 1 and initiated Part 2 (the 52-week blinded dose extension phase where all participants received prasinezumab) were included

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4 1 C metabolism and anti-tumor therapy As discussed earlier, enzymes and metabolites involved in the synthesis and utilization of 1 C units are critical drivers of tumorigenesis and progression, either through their canonical enzymatic activities or through non-canonical functions