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CD36-mediated lipid uptake promotes the storage of fatty acids, mitochondrial FAO and OXPHOS, supporting an M2-like, protumor phenotype characterized by the upregulation of anti-inflammatory effectors, such as CD206, arginase-1 (ARG1), IL-10 and TGF [87,88,89,90,91]
Mechanism three (glutathione depletion) : Nervous system disease (substantia nigra GSH is reduced approximately 40 percent at diagnosis), diseases that affect memory, neurological development disorders, mental health issues, ME/CFS, multiple sclerosis, ALS, and multiple chemical sensitivity
The functional gains may be explained by a drop in blood TG levels observed after EGCG and coconut oil treatment [131]