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This change weakens inherent neuroprotective mechanisms including mitochondrial biogenesis, synaptic maintenance, and antioxidant defenses in dopaminergic neurons by reducing their ability to remove pathogenic -synuclein and increasing the release of neurotoxins [135]

37 Nonetheless, EAAT3 has been associated with increased chemoresistance in colorectal cancer models 38 and reported to be highly expressed in prostate cancer

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It promotes lipolysis , the breakdown of triglycerides into free fatty acids used for energy, aiding in reductions in body fat percentage (Yaspelkis & Ivy, American Journal of Physiology )