Dupixent (sBLA), February 28 Regeneron Pharmaceutical For adults and children aged 6 years and older with allergic fungal rhinosinusitis
A study demonstrated that, in a hepatocellular carcinoma model, ferroptotic cells released oxidized phospholipids and DAMPs (such as HMGB1 and 4-HNE), which activated the NLRP3 inflammasome in macrophages
Ingredients: Water, butylene glycol (1,3, butanediol), tocofersolan, hyaluronic acid, ethanol, caprylyl glycol, medium chain triglycerides, copper tripeptide-1 (GHK-Cu), highly purified phospholipids, natural mixed tocopherols, Psoralea corylifolia seed/leaf extract (Bakuchiol), Tetrahexyldecyl ascorbate, lavender essential oil, estriol, estradiol Other Ingredients: None
527,528 Second-line medications Opioids and atypical opioids Tapentadol: A centrally acting analgesic with both opioid agonist and norepinephrine reuptake inhibition properties