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3 Side by side image illustrating unbiased GLP-1RA signalling vs biased receptor modulator and the subsequent limitation of B-arrestin recruitment with retention of cAMP signaling potency 1,6 Reach out to a Genentech Medical Science Liaison near you, or connect with the contact center

Dieting harder, exercising more, and cutting calories isnt working anymore and deep down, youre worried this weight gain is turning into insulin resistance, pre-diabetes, or future health problems

Patients should verify this information before leaving the pharmacy

This suggests retatrutide continues working beyond one year without the plateau seen with some other weight loss interventions