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This indicated a lower influx of proline into the TCA cycle via the glutamate to -ketoglutarate route

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In terms of iron and Alzheimers, they think its irons potential to effectively rust brain tissue by producing free radicals that may cause neurodegeneration, contributing to Alzheimers disease pathology at numerous levelsso much so that there is interest in trying to treat Alzheimers disease by targeting iron