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Most patients experience their first side effects within 24 to 72 hours after the initial injection, though timing varies based on individual metabolism and genetic factors

Specifically, the FDA is requiring Lilly to complete various post-marketing clinical trials of Foundayo to look at the potential risks for various side effects, including cardiovascular events, liver toxicity, and delayed gastric emptying (gastroparesis), as non-clinical or observational studies will not be sufficient

Don't freeze: Freezing reconstituted peptide can cause the solution to form ice crystals that damage the peptide structure when thawed

Trx proteins undergo reversible protein-disulfide exchange reactions with their substrates [1,5]