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A., Neznamov, G

7.3.2.2 In vitro model system development Current efforts to develop organoid models of human testicular tissue remain in early experimental phases, with significant technical challenges limiting their immediate applicability to EED research

DOI: 10.1046/j.1365-313X.1993.04020215.x 82

Consistent with the notion that the PI3K/AKT pathway is the most commonly activated pathway in human cancers [114], AKT-mediated phosphorylation represents the primary mechanism of FOXO inactivation in cancer