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Split dosing does use the vial faster because you puncture the stopper more frequently, increasing contamination exposure slightly

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In sleep deprivation studies, high dose creatine improved cognitive performance even compared to rested baselines She travels with creatine and bumps to 20 to 25 grams when she knows she is going to be sleep deprived Also being researched: mild cognitive impairment, early Alzheimers, TBI recovery in children

Oral supplementation of a either a single antioxidant or a combination of antioxidants such as L-carnitine, L-acetyl carnitine, N-acetyl-cysteine, Coenzyme Q10, selenium, vitamin C, vitamin E, and lycopene has been reported to enhance semen parameters and sperm DNA integrity in idiopathic infertile men [61]