Because targeting glutamine metabolism reduced MDSC recruitment in the lungs before visible metastasis occurs (Figure 2E), we wanted to know whether the metabolic milieu of the TME at the lung metastatic site also plays a critical role in facilitating metastasis
Proton nuclear magnetic resonance ( 1 H NMR, 400 MHz, D 2 O) revealed signals at H 2.21 (q, 2H, H-3), 2.59 (td, 2H, H-4), 2.98 (dd, 2H, CH 2 S), 3.86 (t, 1H, H-2), 4.02 (s, 2H, H-10), and 4.60 (t, 1H, H-7)
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