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This disruption mirrors the ECM abnormalities observed in hEDS, suggesting a shared potential role for mitochondrial dysfunction in connective tissue pathologies

doi:10.1016/j.bbrc.2010.05.108 Angelini G, Gardella S, Ardy M, Ciriolo MR, Filomeni G, Di Trapani G, Clarke F, Sitia R, Rubartelli A (2002) Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation

While unexpected for a transmembrane protein, pU L 34 was also found in a proteomics study of purified HSV-1 nuclear capsids (i.e