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In colon carcinoma HCT116 cells, Chowdhury et al

Common side effects of Ozempic, even when used as intended, include: Nausea Vomiting Diarrhea Constipation Stomach pain These side effects can be more severe or longer lasting when taking Ozempic in higher doses for weight loss

The three LPP family members are PLPP1, PLPP2, and PLPP3 as indicated in the Table below

Gene expression on BDNF and SK-3 was quantified using real-time PCR, revealing that VPA reduced the expression BDNF, which plays a crucial role in synaptic plasticity and neuronal survival, and increased GSK-3, which is involved in neurodevelopment and neuroinflammation whereas crocin dose-dependently normalized both markers (Hosseini et al., 2025)