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doi: 10.1159/000489241

Increased Risk of Hypoglycemia (Low Blood Sugar): While both drugs individually have a lower risk of hypoglycemia compared to some other diabetes medications, combining them, especially if not carefully managed or if lifestyle factors are not optimized, can slightly increase this risk

In skeletal muscle, IGF-1 LR3 activates satellite cells, promoting their proliferation and differentiation into mature muscle fibersa process termed hyperplasia (increase in cell number) distinct from hypertrophy (increase in cell size)

High albumin levels in the brain induce proinflammatory cytokine production and prevent potassium levels from being balanced