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Mood-altering drugs such as SSRIs, benzodiazepines, or antipsychotics do nothing to improve glutathione status, mitochondrial function, or detoxification

In a randomized, double-blind, placebo-controlled pilot trial published in Movement Disorders (2009) by Hauser and colleagues (21 patients), intravenous glutathione at 1,400 mg three times weekly was well tolerated with no withdrawals due to adverse events, although it did not produce statistically significant efficacy differences versus placebo

PMID: 38 Bayet-RobertMKwiatkowskiFLeheurteurMGachonFPlanchatEAbrialCet al

Although research in humans is still very limited, some studies suggest that vitamin B12 could affect body fat and metabolism